PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18406051-5 2008 ROS-dependent angiogenesis can be regulated by endogenous antioxidant enzymes such as SOD and thioredoxin. Reactive Oxygen Species 0-3 thioredoxin Homo sapiens 94-105 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 NADPH oxidase 1 Homo sapiens 64-68 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 cytochrome b-245 beta chain Homo sapiens 70-74 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 NADPH oxidase 4 Homo sapiens 76-80 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 NADPH oxidase 5 Homo sapiens 82-86 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 cytochrome b-245 alpha chain Homo sapiens 88-95 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 neutrophil cytosolic factor 1 Homo sapiens 97-104 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 Rac family small GTPase 2 Homo sapiens 113-128 18406051-7 2008 Major source of ROS in ECs is a NADPH oxidase which consists of Nox1, Nox2, Nox4, Nox5, p22phox, p47phox and the small G-protein Rac1. Reactive Oxygen Species 16-19 Rac family small GTPase 1 Homo sapiens 129-133 18406051-8 2008 NADPH oxidase is activated by various growth factors including VEGF and angiopoietin-1 as well as hypoxia and ischemia, and ROS derived from this oxidase are involved in VEGFR2 autophosphorylation, and diverse redox signaling pathways leading to induction of transcription factors and genes involved in angiogenesis. Reactive Oxygen Species 124-127 vascular endothelial growth factor A Homo sapiens 63-67 18406051-8 2008 NADPH oxidase is activated by various growth factors including VEGF and angiopoietin-1 as well as hypoxia and ischemia, and ROS derived from this oxidase are involved in VEGFR2 autophosphorylation, and diverse redox signaling pathways leading to induction of transcription factors and genes involved in angiogenesis. Reactive Oxygen Species 124-127 angiopoietin 1 Homo sapiens 72-86 18406051-8 2008 NADPH oxidase is activated by various growth factors including VEGF and angiopoietin-1 as well as hypoxia and ischemia, and ROS derived from this oxidase are involved in VEGFR2 autophosphorylation, and diverse redox signaling pathways leading to induction of transcription factors and genes involved in angiogenesis. Reactive Oxygen Species 124-127 kinase insert domain receptor Homo sapiens 170-176