PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18372000-4	2008	In this study, we assessed the effects of CYP1 enzymes (CYP1A1, CYP1A2 and CYP1B1) on BaP-induced AhR transactivation and DNA adduct formation in HEK293 cells and HepG2 cells.	Benzo(a)pyrene	86-89	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	75-81	
18372000-5	2008	Transfection of CYP1A1 and CYP1B1, but not CYP1A2, suppressed BaP-induced activation of AhR.	Benzo(a)pyrene	62-65	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	27-33	
18372000-7	2008	These results indicate that CYP1A1 and CYP1B1 play a role in deactivation of BaP on AhR and that CYP1A1 and CYP1A2 are involved in BaP detoxification by suppressing DNA adduct formation.	Benzo(a)pyrene	77-80	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	39-45	
18372000-10	2008	Dynamic expression of CYP1A1, CYP1A2 and CYP1B1 along with expression of other enzymes such as epoxide hydrolase and phase II enzymes may determine the detoxification or metabolic activation of BaP.	Benzo(a)pyrene	194-197	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	41-47