PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18312488-0	2008	GABA control of GnRH release from the ewe hypothalamus in vitro: sensitivity to oestradiol.	gamma-Aminobutyric Acid	0-4	gonadotropin releasing hormone 1	Homo sapiens	16-20	
18312488-1	2008	The present study examines the involvement of GABA(A or B) receptors in gonadotrophin-releasing hormone (GnRH) release in vitro and determines whether oestradiol modulates gamma-aminobutyric acid (GABA)-GnRH interaction.	gamma-Aminobutyric Acid	172-195	gonadotropin releasing hormone 1	Homo sapiens	203-207	
18312488-1	2008	The present study examines the involvement of GABA(A or B) receptors in gonadotrophin-releasing hormone (GnRH) release in vitro and determines whether oestradiol modulates gamma-aminobutyric acid (GABA)-GnRH interaction.	gamma-Aminobutyric Acid	197-201	gonadotropin releasing hormone 1	Homo sapiens	203-207	
18312488-5	2008	However, GnRH increased (p < 0.05) after exposure to 10 mM GABA(A or B) antagonists (bicuculline or CGP52432, respectively).	gamma-Aminobutyric Acid	62-66	gonadotropin releasing hormone 1	Homo sapiens	9-13	
18312488-6	2008	The GABA(A) antagonist stimulated greater sustained GnRH release (p < 0.05) in the absence of oestradiol than in its presence.	gamma-Aminobutyric Acid	4-8	gonadotropin releasing hormone 1	Homo sapiens	52-56	
18312488-8	2008	Only after exposure of hypothalamic slices to the GABA(A) antagonist, did the hypothalamic eluate stimulate luteinizing hormone release from pituitary fragments (p < 0.05) confirming that the GABA(A) antagonist stimulated release of biologically active GnRH.	gamma-Aminobutyric Acid	50-54	gonadotropin releasing hormone 1	Homo sapiens	256-260	
18312488-9	2008	In summary, GnRH release from the hypothalamus is predominantly under GABA(A) receptor inhibitory control and this is attenuated in the presence of oestradiol.	gamma-Aminobutyric Acid	70-74	gonadotropin releasing hormone 1	Homo sapiens	12-16