PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18036351-6 2008 In contrast, overexpression of the proline biosynthetic enzymes Delta(1)-pyrroline-5-carboxylate (P5C) synthetase (P5CS) and P5C reductase (P5CR) resulted in 2-fold higher proline content, significantly lower ROS levels, and increased cell survival relative to control cells. Proline 35-42 aldehyde dehydrogenase 18 family member A1 Homo sapiens 115-119 18036351-6 2008 In contrast, overexpression of the proline biosynthetic enzymes Delta(1)-pyrroline-5-carboxylate (P5C) synthetase (P5CS) and P5C reductase (P5CR) resulted in 2-fold higher proline content, significantly lower ROS levels, and increased cell survival relative to control cells. Proline 172-179 aldehyde dehydrogenase 18 family member A1 Homo sapiens 115-119 18036351-7 2008 In different mammalian cell lines exposed to physiological H(2)O(2) levels, increased endogenous P5CS and P5CR expression was observed, indicating that upregulation of proline biosynthesis is an oxidative stress response. Proline 168-175 aldehyde dehydrogenase 18 family member A1 Homo sapiens 97-101