PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17997002-0	2008	Arecoline-induced growth arrest and p21WAF1 expression are dependent on p53 in rat hepatocytes.	Arecoline	0-9	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	72-75	
17997002-7	2008	Moreover, arecoline (0.5mM) time-dependently (8-24h) increased p53 serine 15 phosphorylation.	Arecoline	10-19	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	63-66	
17997002-8	2008	Pifithrin-alpha (p53 inhibitor) and the loss of the two p53-binding elements in the p21(WAF1) gene promoter attenuated arecoline-induced p21(WAF1) gene transcription at 24h.	Arecoline	119-128	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	17-20	
17997002-8	2008	Pifithrin-alpha (p53 inhibitor) and the loss of the two p53-binding elements in the p21(WAF1) gene promoter attenuated arecoline-induced p21(WAF1) gene transcription at 24h.	Arecoline	119-128	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	56-59	
17997002-10	2008	We concluded that arecoline induces cytotoxicity, DNA damage, G(0)/G(1) cell cycle arrest, TGF-beta1, p21(WAF1) and activates p53 in Clone-9 cells.	Arecoline	18-27	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	126-129	
17997002-11	2008	Moreover, arecoline-induced p21(WAF1) is dependent on p53 while arecoline-inhibited growth is dependent on both TGF-beta and p53.	Arecoline	10-19	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	54-57	
17997002-11	2008	Moreover, arecoline-induced p21(WAF1) is dependent on p53 while arecoline-inhibited growth is dependent on both TGF-beta and p53.	Arecoline	64-73	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	125-128