PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17996985-5 2008 Wortmannin (10 nM) and LY 294002 (10 microM) (inhibitors of phosphatidylinositol-3-kinase, PI3-K) reversed the inhibitory effect of memantine on the staurosporine-induced LDH release, suggesting that the PI3-K/Akt prosurvival pathway is a possible target for antiapoptotic action of memantine. Staurosporine 149-162 AKT serine/threonine kinase 1 Homo sapiens 210-213