PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17827720-0 2007 Enhanced expression of membrane-associated sialidase Neu3 decreases GD3 and increases GM3 on the surface of Jurkat cells during etoposide-induced apoptosis. Etoposide 128-137 neuraminidase 3 Homo sapiens 53-57 17827720-7 2007 Furthermore, etoposide caused a gradual up-regulation of Neu3 mRNA expression but not Neu1 mRNA expression. Etoposide 13-22 neuraminidase 3 Homo sapiens 57-61 17827720-9 2007 These results indicate that Neu3 is up-regulated in Jurkat cells undergoing etoposide-induced apoptosis through intracellular signaling events downstream of caspase 3 activation and that enhanced Neu3 activity is closely related to the changes of cell surface ganglioside composition. Etoposide 76-85 neuraminidase 3 Homo sapiens 28-32