PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1761576-0 1991 Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration. Guanine Nucleotides 0-18 transformation related protein 53, pseudogene Mus musculus 61-64 1761576-3 1991 The reversal of the induction phenotype by these purine salvage precursors implicated the purine nucleotide biosynthetic pathway as the cellular target for the antiproliferative action of p53. purine 49-55 transformation related protein 53, pseudogene Mus musculus 188-191 1761576-3 1991 The reversal of the induction phenotype by these purine salvage precursors implicated the purine nucleotide biosynthetic pathway as the cellular target for the antiproliferative action of p53. Purine Nucleotides 90-107 transformation related protein 53, pseudogene Mus musculus 188-191 1761576-4 1991 Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. purine 79-85 transformation related protein 53, pseudogene Mus musculus 57-60 1761576-4 1991 Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. Inosine Monophosphate 136-160 transformation related protein 53, pseudogene Mus musculus 57-60 1761576-4 1991 Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. xanthosine monophosphate 175-202 transformation related protein 53, pseudogene Mus musculus 57-60 1761576-7 1991 These findings define p53 as a cellular regulator of the synthesis of GTP, a key regulatory nucleotide for many important cellular processes. Guanosine Triphosphate 70-73 transformation related protein 53, pseudogene Mus musculus 22-25 1761576-8 1991 Moreover, observations of the growth behavior of p53-inducible cells suggest that by regulating the production of GTP, p53 can control cellular quiescence. Guanosine Triphosphate 114-117 transformation related protein 53, pseudogene Mus musculus 49-52 1761576-8 1991 Moreover, observations of the growth behavior of p53-inducible cells suggest that by regulating the production of GTP, p53 can control cellular quiescence. Guanosine Triphosphate 114-117 transformation related protein 53, pseudogene Mus musculus 119-122