PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17604010-0 2007 Influence of chloride on modification of unsaturated phosphatidylcholines by the myeloperoxidase/hydrogen peroxide/bromide system. Chlorides 13-21 myeloperoxidase Homo sapiens 81-96 17604010-1 2007 The leukocyte enzyme myeloperoxidase (MPO) is capable of catalyzing the oxidation of chloride and bromide ions, at physiological concentrations of these substrates, by hydrogen peroxide, generating hypochlorous acid (HOCl) and hypobromous acid (HOBr), respectively. Chlorides 85-93 myeloperoxidase Homo sapiens 21-36 17604010-1 2007 The leukocyte enzyme myeloperoxidase (MPO) is capable of catalyzing the oxidation of chloride and bromide ions, at physiological concentrations of these substrates, by hydrogen peroxide, generating hypochlorous acid (HOCl) and hypobromous acid (HOBr), respectively. Chlorides 85-93 myeloperoxidase Homo sapiens 38-41 17604010-4 2007 This study was conducted to determine the effect physiological chloride concentration (140 mM) has on the formation of bromohydrins and lyso-PC from unsaturated PC upon treatment with the myeloperoxidase/hydrogen peroxide/bromide (MPO/H2O2/Br-) system using physiological bromide concentrations (20-100 microM). Chlorides 63-71 myeloperoxidase Homo sapiens 188-203 17604010-4 2007 This study was conducted to determine the effect physiological chloride concentration (140 mM) has on the formation of bromohydrins and lyso-PC from unsaturated PC upon treatment with the myeloperoxidase/hydrogen peroxide/bromide (MPO/H2O2/Br-) system using physiological bromide concentrations (20-100 microM). Chlorides 63-71 myeloperoxidase Homo sapiens 231-234 17604010-11 2007 The results indicate that at physiological levels of chloride and bromide, chloride promotes MPO-mediated formation of bromohydrins and lyso-PC in unsaturated phospholipids. Chlorides 53-61 myeloperoxidase Homo sapiens 93-96 17604010-11 2007 The results indicate that at physiological levels of chloride and bromide, chloride promotes MPO-mediated formation of bromohydrins and lyso-PC in unsaturated phospholipids. Chlorides 75-83 myeloperoxidase Homo sapiens 93-96