PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17535976-0 2007 Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation. Reactive Oxygen Species 156-179 proline dehydrogenase 1 Homo sapiens 132-147 17535976-5 2007 Reactive oxygen species (ROS) production was accompanied by increased expression of proline oxidase (POX), a redox enzyme expressed in mitochondria, upon incubation with the agonists. Reactive Oxygen Species 0-23 proline dehydrogenase 1 Homo sapiens 84-99 17535976-5 2007 Reactive oxygen species (ROS) production was accompanied by increased expression of proline oxidase (POX), a redox enzyme expressed in mitochondria, upon incubation with the agonists. Reactive Oxygen Species 0-23 proline dehydrogenase 1 Homo sapiens 101-104 17535976-5 2007 Reactive oxygen species (ROS) production was accompanied by increased expression of proline oxidase (POX), a redox enzyme expressed in mitochondria, upon incubation with the agonists. Reactive Oxygen Species 25-28 proline dehydrogenase 1 Homo sapiens 84-99 17535976-5 2007 Reactive oxygen species (ROS) production was accompanied by increased expression of proline oxidase (POX), a redox enzyme expressed in mitochondria, upon incubation with the agonists. Reactive Oxygen Species 25-28 proline dehydrogenase 1 Homo sapiens 101-104 17535976-6 2007 POX RNA interference treatment blocked PPARgamma-induced ROS formation and cytotoxicity, suggesting that POX plays a functional role in apoptosis through ROS formation. Reactive Oxygen Species 57-60 proline dehydrogenase 1 Homo sapiens 0-3 17535976-6 2007 POX RNA interference treatment blocked PPARgamma-induced ROS formation and cytotoxicity, suggesting that POX plays a functional role in apoptosis through ROS formation. Reactive Oxygen Species 57-60 proline dehydrogenase 1 Homo sapiens 105-108 17535976-6 2007 POX RNA interference treatment blocked PPARgamma-induced ROS formation and cytotoxicity, suggesting that POX plays a functional role in apoptosis through ROS formation. Reactive Oxygen Species 154-157 proline dehydrogenase 1 Homo sapiens 0-3 17535976-6 2007 POX RNA interference treatment blocked PPARgamma-induced ROS formation and cytotoxicity, suggesting that POX plays a functional role in apoptosis through ROS formation. Reactive Oxygen Species 154-157 proline dehydrogenase 1 Homo sapiens 105-108 17535976-8 2007 The results of the present study suggest that PPARgamma activation induces apoptotic cell death in non-small-cell lung carcinoma mainly through ROS formation via POX induction. Reactive Oxygen Species 144-147 proline dehydrogenase 1 Homo sapiens 162-165