PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17507616-7 2007 These results support the hypothesis that the formation and accumulation of catechol estrogens in breast tissue through increased CYP1B1 expression and reduced COMT expression may play a significant role in breast cancer risk. catechol 76-84 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 130-136