PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17431132-0 2007 Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. Imatinib Mesylate 138-155 nibrin Homo sapiens 28-32 17431132-0 2007 Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. Imatinib Mesylate 138-155 MRE11 homolog, double strand break repair nuclease Homo sapiens 76-81 17431132-0 2007 Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. Imatinib Mesylate 138-155 RAD50 double strand break repair protein Homo sapiens 82-87 17431132-0 2007 Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. Imatinib Mesylate 138-155 nibrin Homo sapiens 88-92 17431132-0 2007 Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells. Imatinib Mesylate 138-155 BCR activator of RhoGEF and GTPase Homo sapiens 164-167 17431132-4 2007 Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Serine 57-63 nibrin Homo sapiens 49-53 17431132-4 2007 Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Serine 57-63 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 152-159 17431132-4 2007 Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Serine 57-63 interleukin 3 Homo sapiens 228-232 17431132-4 2007 Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Serine 57-63 colony stimulating factor 2 Homo sapiens 234-240 17431132-4 2007 Enhanced ATM kinase-dependent phosphorylation of Nbs1 on serine 343 (S343) in response to genotoxic treatment was detected in leukemia cells expressing BCR/ABL and other FTKs in comparison to normal counterparts stimulated with IL-3, GM-CSF, and SCF. Serine 57-63 KIT ligand Homo sapiens 246-249 17431132-6 2007 Interestingly, inhibition of Nbs1 phosphorylation by S343A mutant enhanced the antileukemia effect of the combination of imatinib and genotoxic agent. Imatinib Mesylate 121-129 nibrin Homo sapiens 29-33