PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17363476-3 2007 Radiation causes a rapid reactive oxygen species-dependent activation of ERBB family and other tyrosine kinases, leading to activation of RAS proteins and multiple protective downstream signaling pathways (e.g., AKT and ERK1/2), which alter transcription factor function and the apoptotic threshold of cells. Reactive Oxygen Species 25-48 mitogen-activated protein kinase 3 Homo sapiens 220-226