PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17179942-0	2007	Effects of budesonide on P-glycoprotein expression in intestinal cell lines.	Budesonide	11-21	ATP binding cassette subfamily B member 1	Homo sapiens	25-39	
17179942-2	2007	Since glucocorticoids, such as budesonide, are frequently used during inflammatory bowel disease we investigated how budesonide influences P-gp expression in different intestinal cell lines.	Budesonide	117-127	ATP binding cassette subfamily B member 1	Homo sapiens	139-143	
17179942-6	2007	KEY RESULTS: Budesonide showed an induction of P-gp in LS180 cells and a down-regulation in Caco-2 cells.	Budesonide	13-23	ATP binding cassette subfamily B member 1	Homo sapiens	47-51	
17179942-9	2007	In PXR-transfected Caco-2 cells the budesonide-mediated down-regulation of P-gp was abolished.	Budesonide	36-46	ATP binding cassette subfamily B member 1	Homo sapiens	75-79	
17179942-11	2007	CONCLUSIONS AND IMPLICATIONS: Budesonide has the potential to influence MDR1 expression in vitro.	Budesonide	30-40	ATP binding cassette subfamily B member 1	Homo sapiens	72-76	
17179942-12	2007	In LS180 cells, the induction of MDR1 by budesonide probably is mediated via PXR.	Budesonide	41-51	ATP binding cassette subfamily B member 1	Homo sapiens	33-37	
17179942-14	2007	Further studies are required to evaluate how budesonide alters P-gp expression in vivo.	Budesonide	45-55	ATP binding cassette subfamily B member 1	Homo sapiens	63-67