PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16984258-0	2006	Activation of platelet-activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 production.	Dinoprostone	105-121	PCNA clamp associated factor	Homo sapiens	14-40	
16984258-1	2006	Platelet-activating factor (PAF) is a group of phosphocholines with various biological effects mediated by the PAF receptor (PAF-R).	Phosphorylcholine	47-62	PCNA clamp associated factor	Homo sapiens	0-26	
16984258-1	2006	Platelet-activating factor (PAF) is a group of phosphocholines with various biological effects mediated by the PAF receptor (PAF-R).	Phosphorylcholine	47-62	PCNA clamp associated factor	Homo sapiens	28-31	
16984258-1	2006	Platelet-activating factor (PAF) is a group of phosphocholines with various biological effects mediated by the PAF receptor (PAF-R).	Phosphorylcholine	47-62	platelet activating factor receptor	Homo sapiens	111-123	
16984258-1	2006	Platelet-activating factor (PAF) is a group of phosphocholines with various biological effects mediated by the PAF receptor (PAF-R).	Phosphorylcholine	47-62	platelet activating factor receptor	Homo sapiens	125-130	
16984258-2	2006	Activation of the epidermal PAF-R induces the expression of inflammatory mediators, including cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)).	Dinoprostone	123-141	platelet activating factor receptor	Homo sapiens	28-33	
16984258-2	2006	Activation of the epidermal PAF-R induces the expression of inflammatory mediators, including cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)).	Prostaglandins E	143-146	platelet activating factor receptor	Homo sapiens	28-33	
16984258-4	2006	The present study was designed to investigate whether PAF-R activation could induce the expression of COX-2 and production of PGE(2), as well as secretion of the inflammatory cytokine, interleukin-8 (IL-8), in the immortalized sebaceous gland cell line SZ95.	Dinoprostone	126-132	platelet activating factor receptor	Homo sapiens	54-59	
16984258-5	2006	Using calcium mobilization studies, we first confirmed that PAF can signal through PAF-R in SZ95 sebocytes.	Calcium	6-13	PCNA clamp associated factor	Homo sapiens	60-63	
16984258-8	2006	Finally, it was demonstrated that the production of PGE(2), induced by PAF-R activation and mediated by COX-2 expression, was blocked following PAF-R antagonism in SZ95 sebocytes.	Prostaglandins E	52-55	platelet activating factor receptor	Homo sapiens	71-76	
16984258-8	2006	Finally, it was demonstrated that the production of PGE(2), induced by PAF-R activation and mediated by COX-2 expression, was blocked following PAF-R antagonism in SZ95 sebocytes.	Prostaglandins E	52-55	prostaglandin-endoperoxide synthase 2	Homo sapiens	104-109	
16984258-8	2006	Finally, it was demonstrated that the production of PGE(2), induced by PAF-R activation and mediated by COX-2 expression, was blocked following PAF-R antagonism in SZ95 sebocytes.	Prostaglandins E	52-55	platelet activating factor receptor	Homo sapiens	144-149	
16984258-9	2006	These studies suggest that SZ95 sebocytes express functional PAF-Rs and PAF-Rs are involved in regulating the expression of inflammatory mediators, including COX-2, PGE(2) and IL-8.	Prostaglandins E	165-168	PCNA clamp associated factor	Homo sapiens	61-64	
16984258-9	2006	These studies suggest that SZ95 sebocytes express functional PAF-Rs and PAF-Rs are involved in regulating the expression of inflammatory mediators, including COX-2, PGE(2) and IL-8.	Prostaglandins E	165-168	PCNA clamp associated factor	Homo sapiens	72-75