PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1668725-3	1991	The cytotoxicity of gamma-IFN and TNF-alpha could be reversed in all cells by the addition of L- or D-tryptophan to the culture medium.	l- or d-tryptophan	94-112	tumor necrosis factor	Homo sapiens	34-43	
1668725-4	1991	Melanoma cells resistant to gamma-IFN excrete calcium activated neutral protease (CANP) and as a consequence, make L-tryptophan available by the hydrolysis of serum proteins in the culture medium.	Tryptophan	115-127	calpain 1	Homo sapiens	46-80	
1668725-4	1991	Melanoma cells resistant to gamma-IFN excrete calcium activated neutral protease (CANP) and as a consequence, make L-tryptophan available by the hydrolysis of serum proteins in the culture medium.	Tryptophan	115-127	calpain 1	Homo sapiens	82-86	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Superoxides	84-86	tumor necrosis factor	Homo sapiens	0-9	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Superoxides	84-86	superoxide dismutase 2	Homo sapiens	18-59	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Superoxides	84-86	superoxide dismutase 2	Homo sapiens	61-66	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Hydrogen Peroxide	127-144	tumor necrosis factor	Homo sapiens	0-9	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Hydrogen Peroxide	127-144	superoxide dismutase 2	Homo sapiens	18-59	
1668725-9	1991	TNF-alpha induces manganese-containing superoxide dismutase (MnSOD) which also uses O2- to produce cytotoxic concentrations of hydrogen peroxide.	Hydrogen Peroxide	127-144	superoxide dismutase 2	Homo sapiens	61-66	
1668725-10	1991	Therefore, it can be concluded that the cytotoxicity of both gamma-IFN and TNF-alpha depends on the availability of L-tryptophan as the substrate for the removal of O2- via indoleamine 2,3-dioxygenase.	Tryptophan	116-128	tumor necrosis factor	Homo sapiens	75-84	
1668725-10	1991	Therefore, it can be concluded that the cytotoxicity of both gamma-IFN and TNF-alpha depends on the availability of L-tryptophan as the substrate for the removal of O2- via indoleamine 2,3-dioxygenase.	Superoxides	165-167	tumor necrosis factor	Homo sapiens	75-84