PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16564524-7 2006 These results show for the first time a direct osteogenic effect of metformin on osteoblasts in culture, which could be mediated by activation/redistribution of ERK-1/2 and induction of e/iNOS. Metformin 68-77 mitogen-activated protein kinase 3 Homo sapiens 161-168