PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16461916-6 2006 We mutated one such buried pair, Tyr-236 and Thr-253 to Phe-236 and Ile-253 (as found in the paralogs p63 and p73), and stabilized p53 by 1.6 kcal/mol. Isoleucine 68-71 tumor protein p53 Homo sapiens 131-134