PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16415089-0	2006	Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum.	Clozapine	0-9	dopa decarboxylase	Mus musculus	20-55	
16415089-3	2006	A single dose of clozapine increased AAAD activity of striatum in a dose- and time-dependent manner.	Clozapine	17-26	dopa decarboxylase	Mus musculus	37-41	
16415089-5	2006	Acute clozapine increased tyrosine hydroxylase activity in striatum but with differing temporal patterns from AAAD and heightened dopamine metabolism.	Clozapine	6-15	dopa decarboxylase	Mus musculus	110-114	
16415089-7	2006	Chronically administered clozapine increased AAAD activity and protein and dopamine metabolism in striatum without affecting tyrosine hydroxylase.	Clozapine	25-34	dopa decarboxylase	Mus musculus	45-49	
16415089-11	2006	For the first time, these studies provide evidence that clozapine modulates AAAD activity in the brain and suggests that dopamine and serotonin receptors are involved.	Clozapine	56-65	dopa decarboxylase	Mus musculus	76-80