PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16289039-4 2005 In this study, PARP-1 activation by hydrogen peroxide decreased intracellular NAD+ levels in human pulmonary epithelial cells, which was found to be prevented in a dose-dependent manner by theophylline, a widely used compound in the treatment of COPD. Hydrogen Peroxide 36-53 poly(ADP-ribose) polymerase 1 Homo sapiens 15-21