PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1616052-0	1992	Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro.	Phorbol Esters	25-38	superoxide dismutase 2	Homo sapiens	71-76	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Phorbol Esters	48-61	surfactant protein A1	Homo sapiens	180-184	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Phorbol Esters	48-61	surfactant protein B	Homo sapiens	189-193	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Tetradecanoylphorbol Acetate	63-100	surfactant protein A1	Homo sapiens	180-184	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Tetradecanoylphorbol Acetate	63-100	surfactant protein B	Homo sapiens	189-193	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Tetradecanoylphorbol Acetate	102-105	surfactant protein A1	Homo sapiens	180-184	
1616052-1	1992	Tumor necrosis factor-alpha (TNF-alpha) and the phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) decrease the synthesis of surfactant proteins association with decreased SP-A and SP-B mRNA.	Tetradecanoylphorbol Acetate	102-105	surfactant protein B	Homo sapiens	189-193	
1616052-3	1992	SP-A gene transcription was inhibited by both TNF-alpha and TPA as assessed by nuclear run-on assays.	Tetradecanoylphorbol Acetate	60-63	surfactant protein A1	Homo sapiens	0-4	
1616052-4	1992	Inhibitory effects of both agents on SP-A gene transcription were readily detected within 6 h after exposure and persisted for 24 h. While TNF-alpha and TPA decreased cellular SP-B mRNA content, transcription of the SP-B gene was not influenced by these agents.	Tetradecanoylphorbol Acetate	153-156	surfactant protein A1	Homo sapiens	37-41	
1616052-4	1992	Inhibitory effects of both agents on SP-A gene transcription were readily detected within 6 h after exposure and persisted for 24 h. While TNF-alpha and TPA decreased cellular SP-B mRNA content, transcription of the SP-B gene was not influenced by these agents.	Tetradecanoylphorbol Acetate	153-156	surfactant protein B	Homo sapiens	176-180	
1616052-5	1992	In contrast to the inhibitory effects of TPA and TNF-alpha on SP-A and SP-B mRNAs, steady-state mRNA and rate of transcription of human manganese superoxide dismutase (MnSOD) were increased by both agents.	Tetradecanoylphorbol Acetate	41-44	surfactant protein A1	Homo sapiens	62-66	
1616052-5	1992	In contrast to the inhibitory effects of TPA and TNF-alpha on SP-A and SP-B mRNAs, steady-state mRNA and rate of transcription of human manganese superoxide dismutase (MnSOD) were increased by both agents.	Tetradecanoylphorbol Acetate	41-44	surfactant protein B	Homo sapiens	71-75	
1616052-6	1992	The time course and extent of increased MnSOD gene transcription by TNF-alpha and TPA were distinct.	Tetradecanoylphorbol Acetate	82-85	superoxide dismutase 2	Homo sapiens	40-45	
1616052-8	1992	The inhibitory effects of TPA and TNF-alpha on SP-A expression in pulmonary adenocarcinoma cells are associated with the inhibition of SP-A gene transcription.	Tetradecanoylphorbol Acetate	26-29	surfactant protein A1	Homo sapiens	47-51	
1616052-8	1992	The inhibitory effects of TPA and TNF-alpha on SP-A expression in pulmonary adenocarcinoma cells are associated with the inhibition of SP-A gene transcription.	Tetradecanoylphorbol Acetate	26-29	surfactant protein A1	Homo sapiens	135-139	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	tumor necrosis factor	Homo sapiens	48-57	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	69-73	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein B	Homo sapiens	78-82	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	201-205	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein B	Homo sapiens	210-214	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Tetradecanoylphorbol Acetate	62-65	surfactant protein A1	Homo sapiens	69-73	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Tetradecanoylphorbol Acetate	62-65	surfactant protein B	Homo sapiens	78-82	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Tetradecanoylphorbol Acetate	62-65	surfactant protein A1	Homo sapiens	201-205	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Tetradecanoylphorbol Acetate	62-65	surfactant protein B	Homo sapiens	210-214