PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16149076-8 2005 It is thus conferred that such sequent events as ROS production, caspase activation, JNK/SAPK activation, bcl-2 phosphorylation and the further generation of ROS should be parts of an amplification loop to increase caspase activity, thereby facilitating the apoptotic cell death process. Reactive Oxygen Species 158-161 mitogen-activated protein kinase 8 Homo sapiens 85-88