PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16082080-2 2005 We hypothesized that combining low-dose FK506 with anti-CD40 Ligand (anti-CD40L mAb) would enhance regeneration through peripheral nerve allografts while preserving immune unresponsiveness. Tacrolimus 40-45 CD40 ligand Mus musculus 74-79 16082080-5 2005 RESULTS: Animals receiving low-dose FK506 with anti-CD40L mAb exhibited robust nerve regeneration comparable to the isograft and high-dose FK506 allograft groups. Tacrolimus 36-41 CD40 ligand Mus musculus 52-57 16082080-6 2005 Nerve density was significantly increased in the low-dose FK506 with anti-CD40L mAb group compared to animals receiving anti-CD40L mAb alone (p < 0.05). Tacrolimus 58-63 CD40 ligand Mus musculus 74-79 16082080-10 2005 CONCLUSION: When combined with anti-CD40L mAb, low-dose FK506 enhances nerve regeneration without disrupting immune unresponsiveness. Tacrolimus 56-61 CD40 ligand Mus musculus 36-41