PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16049968-5 2006 Here, we demonstrated that FK228 and apicidin exhibited strong resistance in doxorubicin-resistant clones of OS and EFTs expressing P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) and that P-gp and MRP1 might play a crucial role in the resistance mechanism to FK228 and apicidin. Doxorubicin 77-88 ATP binding cassette subfamily C member 1 Homo sapiens 158-199 16049968-5 2006 Here, we demonstrated that FK228 and apicidin exhibited strong resistance in doxorubicin-resistant clones of OS and EFTs expressing P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) and that P-gp and MRP1 might play a crucial role in the resistance mechanism to FK228 and apicidin. Doxorubicin 77-88 ATP binding cassette subfamily C member 1 Homo sapiens 201-205 16049968-5 2006 Here, we demonstrated that FK228 and apicidin exhibited strong resistance in doxorubicin-resistant clones of OS and EFTs expressing P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) and that P-gp and MRP1 might play a crucial role in the resistance mechanism to FK228 and apicidin. Doxorubicin 77-88 ATP binding cassette subfamily C member 1 Homo sapiens 225-229