PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16029119-3 2005 Mutations in six exons (10, 11, 13, 14, 15, and 16) located in either cysteine-rich or tyrosine kinase domains cause one of three distinctive clinical subtypes: familial MTC, multiple endocrine neoplasia (MEN) type 2A (including variants with Hirschsprung"s disease and cutaneous lichen amyloidosis), and MEN 2B. Cysteine 70-78 ret proto-oncogene Homo sapiens 305-311