PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16019190-0	2006	NOX4 as an oxygen sensor to regulate TASK-1 activity.	Oxygen	11-17	NADPH oxidase 4	Homo sapiens	0-4	
16019190-5	2006	In the present study, we propose that the NADPH oxidase NOX4 functions as an oxygen-sensing partner and that it modulates the oxygen sensitivity of TASK-1.	Oxygen	77-83	NADPH oxidase 4	Homo sapiens	56-60	
16019190-5	2006	In the present study, we propose that the NADPH oxidase NOX4 functions as an oxygen-sensing partner and that it modulates the oxygen sensitivity of TASK-1.	Oxygen	126-132	NADPH oxidase 4	Homo sapiens	56-60	
16019190-7	2006	In HEK293 cells expressing NOX4 endogenously, the activity of expressed TASK-1 was moderately inhibited by hypoxia, and this oxygen response was significantly augmented by NOX4.	Oxygen	125-131	NADPH oxidase 4	Homo sapiens	27-31	
16019190-7	2006	In HEK293 cells expressing NOX4 endogenously, the activity of expressed TASK-1 was moderately inhibited by hypoxia, and this oxygen response was significantly augmented by NOX4.	Oxygen	125-131	NADPH oxidase 4	Homo sapiens	172-176	
16019190-8	2006	Moreover, the oxygen sensitivity of TASK-1 was abolished by NOX4 siRNA and NADPH oxidase inhibitors.	Oxygen	14-20	NADPH oxidase 4	Homo sapiens	60-64	
16019190-9	2006	These results suggest a novel function for NOX4 in the oxygen-dependent regulation of TASK-1 activity.	Oxygen	55-61	NADPH oxidase 4	Homo sapiens	43-47