PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15686893-1	2005	Considering importance of developing selective estrogen receptor modulators (SERMs), the present paper explores selectivity requirements of tetrahydroisoquinoline derivatives for binding with ER(alpha) versus ER(beta) receptors using E-state index and physicochemical parameters.	1,2,3,4-tetrahydroisoquinoline	140-162	estrogen receptor 1	Homo sapiens	192-200	
15686893-7	2005	From the analysis it appears that the nitrogen atom of the aminoethoxyphenyl substituent and 6-hydroxy substituent of the tetrahydroisoquinoline nucleus play important roles for ER(alpha)/ER(beta) selectivity in addition to R(1) and R(2) substituents.	1,2,3,4-tetrahydroisoquinoline	122-144	estrogen receptor 1	Homo sapiens	178-187