PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15663890-0	2005	Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum.	Quinolinic Acid	43-58	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	80-83	
15663890-4	2005	The effects of Ac-YVAD-CHO on QA-induced caspase-1 activity, internucleosomal DNA fragmentation, IkappaB-alpha degradation, NF-kappaB, and AP-1 activation, and increases in p53 protein levels were measured with enzyme assays, agarose gel electrophoresis, electrophoresis mobility shift assays, and Western blot analysis.	Quinolinic Acid	30-32	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	173-176	
15663890-6	2005	Ac-YVAD-CHO inhibited QA-induced increases in caspase-1 activity and p53 protein levels, but had no effect on QA-induced IkappaB-alpha degradation, NF-kappaB or AP-1 activation.	Quinolinic Acid	22-24	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	69-72	
15663890-7	2005	CONCLUSION: Caspase-1 is involved in QA-induced p53 upregulation but not IkappaB-alpha degradation.	Quinolinic Acid	37-39	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	48-51