PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15544923-0	2004	Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages.	NADP	106-111	paraoxonase 2	Mus musculus	0-13	
15544923-0	2004	Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages.	NADP	106-111	paraoxonase 2	Mus musculus	15-19	
15544923-4	2004	PON2 expression was analyzed in vitro in THP-1 cells differentiated with 1alpha,25-dihydroxyvitamin D3 and in vivo in mouse peritoneal macrophages (MPM) isolated at increasing time intervals after intraperitoneal thioglycollate injection.	,25-dihydroxyvitamin d3	79-102	paraoxonase 2	Homo sapiens	0-4	
15544923-4	2004	PON2 expression was analyzed in vitro in THP-1 cells differentiated with 1alpha,25-dihydroxyvitamin D3 and in vivo in mouse peritoneal macrophages (MPM) isolated at increasing time intervals after intraperitoneal thioglycollate injection.	Thioglycolates	213-227	paraoxonase 2	Homo sapiens	0-4	
15544923-7	2004	Supplementation of vitamin E to Balb/C mice inhibited the reduced nicotinamide adenine dinuleotide phosphate (NADPH)-oxidase-dependent increase in cellular superoxide anion production by 50% and down-regulated PON2 mRNA expression and activity by 30 and 60%, respectively.	Vitamin E	19-28	paraoxonase 2	Mus musculus	210-214	
15544923-7	2004	Supplementation of vitamin E to Balb/C mice inhibited the reduced nicotinamide adenine dinuleotide phosphate (NADPH)-oxidase-dependent increase in cellular superoxide anion production by 50% and down-regulated PON2 mRNA expression and activity by 30 and 60%, respectively.	NADP	110-115	paraoxonase 2	Mus musculus	210-214	
15544923-9	2004	PON2 expression was found to be regulated, at least in part, by the transcription factor AP-1, as suggested by decreased JDP2 (AP-1 repressor) protein expression in the nucleus and by decreased PON2 expression in the presence of a Jun N-terminal kinase inhibitor (SP600125).	pyrazolanthrone	264-272	paraoxonase 2	Mus musculus	0-4	
15544923-9	2004	PON2 expression was found to be regulated, at least in part, by the transcription factor AP-1, as suggested by decreased JDP2 (AP-1 repressor) protein expression in the nucleus and by decreased PON2 expression in the presence of a Jun N-terminal kinase inhibitor (SP600125).	pyrazolanthrone	264-272	jun proto-oncogene	Mus musculus	89-93	
15544923-11	2004	PON2 stimulation may represent a compensatory mechanism against the increase in cellular superoxide anion production and atherogenesis.	Superoxides	89-105	paraoxonase 2	Mus musculus	0-4