PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1551112-0	1992	Inhibition of p34cdc2 kinase activation, p34cdc2 tyrosine dephosphorylation, and mitotic progression in Chinese hamster ovary cells exposed to etoposide.	Etoposide	143-152	cyclin dependent kinase 1	Homo sapiens	14-21	
1551112-0	1992	Inhibition of p34cdc2 kinase activation, p34cdc2 tyrosine dephosphorylation, and mitotic progression in Chinese hamster ovary cells exposed to etoposide.	Etoposide	143-152	cyclin dependent kinase 1	Homo sapiens	41-48	
1551112-1	1992	p34cdc2 kinase, an enzyme essential for mitosis in mammalian cells, may play a role in etoposide-induced G2 phase arrest of Chinese hamster ovary cells.	Etoposide	87-96	cyclin dependent kinase 1	Homo sapiens	0-7	
1551112-2	1992	In this study, etoposide is shown to cause inhibition of a specific p34cdc2 kinase activation pathway, that of tyrosine dephosphorylation.	Etoposide	15-24	cyclin dependent kinase 1	Homo sapiens	68-75	
1551112-3	1992	Exposure of asynchronously dividing cells to etoposide caused a simultaneous rapid decline of both mitotic index and p34cdc2 kinase activity, suggesting that the kinase was not activated and that the arrest point was in late G2 phase.	Etoposide	45-54	cyclin dependent kinase 1	Homo sapiens	117-124	
1551112-6	1992	A 1-h exposure to etoposide during early G2 phase inhibited p34cdc2 kinase activation, its shift in electrophoretic mobility, and its tyrosine dephosphorylation, all of which correlated with a delay in mitotic progression.	Etoposide	18-27	cyclin dependent kinase 1	Homo sapiens	60-67