PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1534660-5	1992	Consistent with these observations, treatment of rats with loratadine caused a dose-dependent increase in the rate of two reactions that are catalyzed predominantly by 2B1/2, namely testosterone 16 beta-hydroxylation and 7-pentoxyresorufin O-dealkylation.	Loratadine	59-69	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	168-173	
1534660-5	1992	Consistent with these observations, treatment of rats with loratadine caused a dose-dependent increase in the rate of two reactions that are catalyzed predominantly by 2B1/2, namely testosterone 16 beta-hydroxylation and 7-pentoxyresorufin O-dealkylation.	Testosterone	182-194	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	168-173	
1534660-5	1992	Consistent with these observations, treatment of rats with loratadine caused a dose-dependent increase in the rate of two reactions that are catalyzed predominantly by 2B1/2, namely testosterone 16 beta-hydroxylation and 7-pentoxyresorufin O-dealkylation.	pentoxyresorufin	221-239	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	168-173	
1534660-8	1992	As an inducer of P450 3A1/2, loratadine was slightly less effective than phenobarbital, and was considerably less effective than dexamethasone, which caused a 10- to 33-fold increase in testosterone 2 beta-, 6 beta- and 15 beta-hydroxylase activity.	Loratadine	29-39	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	186-239	
1534660-8	1992	As an inducer of P450 3A1/2, loratadine was slightly less effective than phenobarbital, and was considerably less effective than dexamethasone, which caused a 10- to 33-fold increase in testosterone 2 beta-, 6 beta- and 15 beta-hydroxylase activity.	Dexamethasone	129-142	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	186-239