PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15015010-7 2004 Over the course of the study, 83% of patients developed BAbs to IFNbeta-1b, 13% to IM IFNbeta-1a, and 47 % to SC IFNbeta-1a. babs 56-60 interferon beta 1 Homo sapiens 64-71 15015010-13 2004 These findings demonstrate that high titers of both BAbs and NAbs reduce the clinical efficacy of IFNbeta in patients with RRMS, which is important for the long-term efficacy of these drugs. babs 52-56 interferon beta 1 Homo sapiens 98-105