PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14971663-0	2004	Vanadate activated Akt and promoted S phase entry.	Vanadates	0-8	AKT serine/threonine kinase 1	Homo sapiens	19-22	
14971663-6	2004	Furthermore, vanadate increased Akt kinase activity and caused its phosphorylation at Ser473 and Thr308.	Vanadates	13-21	AKT serine/threonine kinase 1	Homo sapiens	32-35	
14971663-7	2004	Inhibition of Akt by either inhibitors or transfected cells with dominant negative kinase mutant or dominant negative phosphorylation mutant decreased the percentage of the cells at the S phase induced by vanadate, and reduced both cyclin E and E2F1 expression and phosphorylation of pRb.	Vanadates	205-213	AKT serine/threonine kinase 1	Homo sapiens	14-17	
14971663-8	2004	The present study indicates that Akt plays an essential role in vanadate-induced increase in cell number at S phase and transition from G1 to S phase through E2F-pRb pathway.	Vanadates	64-72	AKT serine/threonine kinase 1	Homo sapiens	33-36