PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1490432-0	1992	Deficits in cholinergic neurotransmission markers induced by ethylcholine mustard aziridinium (AF64A) in the rat hippocampus: sensitivity to treatment with the monoamine oxidase-B inhibitor L-deprenyl.	ethylcholine aziridinium	95-100	monoamine oxidase B	Rattus norvegicus	160-179	
1490432-0	1992	Deficits in cholinergic neurotransmission markers induced by ethylcholine mustard aziridinium (AF64A) in the rat hippocampus: sensitivity to treatment with the monoamine oxidase-B inhibitor L-deprenyl.	Selegiline	190-200	monoamine oxidase B	Rattus norvegicus	160-179	
1490432-2	1992	administration of ethylcholine mustard aziridinium (AF64A) and of the monoamine oxidase (MAO)-B inhibitor L-deprenyl on the acetylcholine (ACh) biosynthetic enzyme choline acetyltransferase (ChAT), on the ACh catabolic enzyme acetylcholinesterase (AChE) and on the density of ACh muscarinic M-1 and M-2 receptor sites.	Selegiline	106-116	acetylcholinesterase	Rattus norvegicus	248-252	
1490432-2	1992	administration of ethylcholine mustard aziridinium (AF64A) and of the monoamine oxidase (MAO)-B inhibitor L-deprenyl on the acetylcholine (ACh) biosynthetic enzyme choline acetyltransferase (ChAT), on the ACh catabolic enzyme acetylcholinesterase (AChE) and on the density of ACh muscarinic M-1 and M-2 receptor sites.	Acetylcholine	124-137	acetylcholinesterase	Rattus norvegicus	248-252	
1490432-3	1992	In addition, the effect of AF64A and of L-deprenyl treatment on the localization of AChE activity in the CA-1 and CA-3 fields of the hippocampus was evaluated by combined enzyme histochemistry and microdensitometry techniques.	ethylcholine aziridinium	27-32	acetylcholinesterase	Rattus norvegicus	84-88	
1490432-3	1992	In addition, the effect of AF64A and of L-deprenyl treatment on the localization of AChE activity in the CA-1 and CA-3 fields of the hippocampus was evaluated by combined enzyme histochemistry and microdensitometry techniques.	Selegiline	40-50	acetylcholinesterase	Rattus norvegicus	84-88	
1490432-3	1992	In addition, the effect of AF64A and of L-deprenyl treatment on the localization of AChE activity in the CA-1 and CA-3 fields of the hippocampus was evaluated by combined enzyme histochemistry and microdensitometry techniques.	Selegiline	40-50	carbonic anhydrase 1	Rattus norvegicus	105-118	
1490432-5	1992	injection of AF64A induced, 4 weeks after administration of the neurotoxin, a remarkable increase of MAO-B activity, and a significant reduction of ChAT and AChE activities in the hippocampus but not in the neostriatum which was used as a reference tissue.	ethylcholine aziridinium	13-18	monoamine oxidase B	Rattus norvegicus	101-106	
1490432-5	1992	injection of AF64A induced, 4 weeks after administration of the neurotoxin, a remarkable increase of MAO-B activity, and a significant reduction of ChAT and AChE activities in the hippocampus but not in the neostriatum which was used as a reference tissue.	ethylcholine aziridinium	13-18	acetylcholinesterase	Rattus norvegicus	157-161	
1490432-8	1992	Treatment with L-deprenyl induced, from a dose of 11.17 microM/kg/day, a significant reduction of MAO-B activity in the hippocampus.	Selegiline	15-25	monoamine oxidase B	Rattus norvegicus	98-103	
1490432-9	1992	The expression of ChAT and AChE, as well as the density of M-2 receptors, was increased after L-deprenyl administration in the hippocampus but not in the neostriatum.	Selegiline	94-104	acetylcholinesterase	Rattus norvegicus	27-31	
1490432-10	1992	An increase in AChE reactivity was noticeable in the CA-1 and CA-3 fields of the hippocampus of AF64A-injected rats treated with L-deprenyl.	Selegiline	129-139	acetylcholinesterase	Rattus norvegicus	15-19	
1490432-10	1992	An increase in AChE reactivity was noticeable in the CA-1 and CA-3 fields of the hippocampus of AF64A-injected rats treated with L-deprenyl.	Selegiline	129-139	carbonic anhydrase 1	Rattus norvegicus	53-66