PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1465135-1 1992 The mammalian shc gene encodes two overlapping, widely expressed proteins of 46 and 52K, with a carboxy-terminal SH2 domain that binds activated growth factor receptors, and a more amino-terminal glycine/proline-rich region. Glycine 196-203 SHC adaptor protein 1 Homo sapiens 14-17 1465135-1 1992 The mammalian shc gene encodes two overlapping, widely expressed proteins of 46 and 52K, with a carboxy-terminal SH2 domain that binds activated growth factor receptors, and a more amino-terminal glycine/proline-rich region. Proline 204-211 SHC adaptor protein 1 Homo sapiens 14-17 1465135-3 1992 Shc proteins become phosphorylated on tyrosine in cells stimulated with a variety of growth factors, and in cells transformed by v-src (ref. Tyrosine 38-46 SHC adaptor protein 1 Homo sapiens 0-3 1465135-5 1992 Here we report that tyrosine-phosphorylated Shc proteins form a specific complex with a non-phosphorylated 23K polypeptide encoded by the grb2/sem-5 gene. Tyrosine 20-28 SHC adaptor protein 1 Homo sapiens 44-47 1465135-5 1992 Here we report that tyrosine-phosphorylated Shc proteins form a specific complex with a non-phosphorylated 23K polypeptide encoded by the grb2/sem-5 gene. Tyrosine 20-28 growth factor receptor bound protein 2 Homo sapiens 138-142 1465135-5 1992 Here we report that tyrosine-phosphorylated Shc proteins form a specific complex with a non-phosphorylated 23K polypeptide encoded by the grb2/sem-5 gene. Tyrosine 20-28 Sex muscle abnormal protein 5 Caenorhabditis elegans 143-148 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 SHC adaptor protein 1 Homo sapiens 27-30 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 growth factor receptor bound protein 2 Homo sapiens 87-91 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 Sex muscle abnormal protein 5 Caenorhabditis elegans 92-97 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 SHC adaptor protein 1 Homo sapiens 122-125 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 growth factor receptor bound protein 2 Homo sapiens 126-130 1465135-8 1992 These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. Tyrosine 31-39 Sex muscle abnormal protein 5 Caenorhabditis elegans 131-136