PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14551502-2 2003 DPD-inhibiting oral fluoropyrimidines showing promise in early clinical studies included UFT (the 5-FU prodrug, tegafur, plus the DPD substrate, uracil), eniluracil (an irreversible DPD inhibitor that improves the oral bioavailability of 5-FU) and S-1 (tegafur plus a reversible DPD inhibitor, 5-chloro-2,4-dihydroxypyridine, and oxonic acid). Tegafur 89-92 dihydropyrimidine dehydrogenase Homo sapiens 0-3