PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14528517-8 2003 FK506 caused a marked reduction of TNF-a and IL-1beta levels in paw tissue even in short-term (3-day) therapeutic treatment. Tacrolimus 0-5 interleukin 1 beta Rattus norvegicus 45-53 14528517-12 2003 CONCLUSION: FK506 is more effective than MTX in reducing elevated levels of inflammatory cytokines TNF-a, IL-1beta, and IL-6 in established stages of AIA. Tacrolimus 12-17 interleukin 1 beta Rattus norvegicus 106-114