PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14526176-5 2003 SCA7 has a number of features in common with other diseases with polyglutamine expansions: (i) the appearance of clinical symptoms above a threshold number of CAG repeats (>35); (ii) a correlation between the size of the expansion and the rate of progression of the disease: the larger the repeat, the faster the progression; (iii) instability of the repeat sequence (approximately 12 CAG/transmission) that accounts for the marked anticipation of approximately 20 years/generation. polyglutamine 65-78 ataxin 7 Homo sapiens 0-4