PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1431598-0 1992 Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat. Taurocholic Acid 37-49 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 96-127 1431598-5 1992 Cholesterol 7 alpha-hydroxylase activity increased 4-fold with cholestyramine and 29% during cholesterol feeding, but decreased 64% with taurocholate. Taurocholic Acid 137-149 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 0-31 1431598-6 1992 Cholesterol 7 alpha-hydroxylase mRNA levels rose 150% and 50% with cholestyramine and cholesterol feeding, respectively, but decreased 73% with taurocholate. Taurocholic Acid 144-156 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 0-31 1431598-7 1992 The administration of cholesterol together with taurocholate prevented the decline in cholesterol 7 alpha-hydroxylase mRNA levels, but inhibition of enzyme activity persisted (-76%). Taurocholic Acid 48-60 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 86-117