PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 13964-3 1976 Theophylline, which acts to increase cyclic AMP by inhibition of phosphodiesterase and beta 2 adrenergic agents which increase cyclic AMP by stimulating adenylate cyclase, are the mainstays of asthma therapy. Theophylline 0-12 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 87-93 13964-5 1976 Persistent symptoms with adequate theophylline levels (10-20 mug/ml) indicates the need for a beta 2 adrenergic agent by aerosol or orally as a supplement. Theophylline 34-46 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 94-100