PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1374948-8	1992	FK506 pretreatment significantly reduced the serum levels of BUN (P less than 0.02), creatinine (P less than 0.02), and TNF (P less than 0.05) as compared with that seen in controls.	Tacrolimus	0-5	tumor necrosis factor	Rattus norvegicus	120-123	
1374948-11	1992	Based upon these data, it can be concluded that (1) FK506 pretreatment ameliorates the functional renal injury associated with I/R, (2) renal ischemia induces the release of TNF, and (3) FK506 pretreatment results in a significant inhibition of TNF production.	Tacrolimus	52-57	tumor necrosis factor	Rattus norvegicus	174-177	
1374948-11	1992	Based upon these data, it can be concluded that (1) FK506 pretreatment ameliorates the functional renal injury associated with I/R, (2) renal ischemia induces the release of TNF, and (3) FK506 pretreatment results in a significant inhibition of TNF production.	Tacrolimus	52-57	tumor necrosis factor	Rattus norvegicus	245-248