PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1371775-2 1992 In our pursuit of cytokines affecting basophil function, we studied the effect of MCAF on histamine secretion from basophils. Histamine 90-99 C-C motif chemokine ligand 2 Homo sapiens 82-86 1371775-4 1992 MCAF caused dose-dependent release of histamine at concentrations of 10(-8) and 10(-7) M, and the mean release was 31.25 +/- 2.9% at the highest concentration. Histamine 38-47 C-C motif chemokine ligand 2 Homo sapiens 0-4 1371775-5 1992 In the same experiments the mean histamine release by anti-IgE and histamine releasing factor (HRF) was 27.05 +/- 4% and 32.70 +/- 2.7%, respectively. Histamine 33-42 tumor protein, translationally-controlled 1 Homo sapiens 67-93 1371775-5 1992 In the same experiments the mean histamine release by anti-IgE and histamine releasing factor (HRF) was 27.05 +/- 4% and 32.70 +/- 2.7%, respectively. Histamine 33-42 tumor protein, translationally-controlled 1 Homo sapiens 95-98 1371775-6 1992 All 20 subjects responded to MCAF with significant histamine release. Histamine 51-60 C-C motif chemokine ligand 2 Homo sapiens 29-33 1371775-8 1992 The histamine release was significantly correlated between MCAF and HRF (P less than 0.01), but not between MCAF and anti-IgE (P greater than 0.05). Histamine 4-13 C-C motif chemokine ligand 2 Homo sapiens 59-63 1371775-8 1992 The histamine release was significantly correlated between MCAF and HRF (P less than 0.01), but not between MCAF and anti-IgE (P greater than 0.05). Histamine 4-13 tumor protein, translationally-controlled 1 Homo sapiens 68-71 1371775-9 1992 The histamine release by MCAF was complete within the first 3 min. Histamine 4-13 C-C motif chemokine ligand 2 Homo sapiens 25-29 1371775-10 1992 MCAF-induced degranulation was a calcium-dependent process. Calcium 33-40 C-C motif chemokine ligand 2 Homo sapiens 0-4