PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	83-92	C-C motif chemokine ligand 2	Homo sapiens	12-50	
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	83-92	C-C motif chemokine ligand 2	Homo sapiens	52-56	
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	218-227	C-C motif chemokine ligand 2	Homo sapiens	12-50	
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	218-227	C-C motif chemokine ligand 2	Homo sapiens	52-56	
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	291-300	C-C motif chemokine ligand 2	Homo sapiens	12-50	
1370686-1	1992	Recombinant monocyte chemotactic-activating factor (MCAF) has been shown to induce histamine release from human basophils with a dose response between 10(-9) and 10(-6) M. The peak of activity was reached at 10(-7) M. Histamine release by MCAF was rapid with an initial rate comparable with histamine release by an optimal dose of anti-IgE.	Histamine	291-300	C-C motif chemokine ligand 2	Homo sapiens	52-56	
1370686-2	1992	MCAF led to peak histamine release within 1 min.	Histamine	17-26	C-C motif chemokine ligand 2	Homo sapiens	0-4	
1370686-4	1992	The percentage histamine release by MCAF was, however, less than that seen with anti-IgE or FMLP, but this was attributable to a lesser percent release in nonatopic subjects; atopic subjects responded similarly to all three agonists.	Histamine	15-24	C-C motif chemokine ligand 2	Homo sapiens	36-40	
1370686-6	1992	At a suboptimal concentration (2.5 x 10(-9) M), MCAF was unable to prime the basophil to histamine release by other secretagogues.	Histamine	89-98	C-C motif chemokine ligand 2	Homo sapiens	48-52