PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1330291-1 1992 In order to clarify the significance of mutation of the p53 tumor suppressor gene in the genesis and development of human hepatocellular carcinoma (HCC) in an aflatoxin B1 low-exposure area, the spectrum, i.e., incidence, type, and site, of p53 gene mutations was examined in 169 tissue samples resected mainly from Japanese patients using single-strand conformation polymorphism analysis and direct sequencing. Aflatoxin B1 159-171 tumor protein p53 Homo sapiens 56-59