PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1314821-0 1992 Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes. Hydroxyl Radical 53-69 myeloperoxidase Homo sapiens 27-42 1314821-6 1992 Detection of hydroxyl radical from stimulated monocyte-derived macrophages, which lack myeloperoxidase, required the addition of supplemental iron. Hydroxyl Radical 13-29 myeloperoxidase Homo sapiens 87-102 1314821-7 1992 The addition of purified myeloperoxidase to an enzymatic superoxide generating system resulted in the detection of hydroxyl radical that was dependent upon the presence of chloride and was inhibited by superoxide dismutase, catalase, and azide. Hydroxyl Radical 115-131 myeloperoxidase Homo sapiens 25-40 1314821-9 1992 4-POBN-CH(CH3)OH was not observed upon stimulation of myeloperoxidase-deficient neutrophils, whereas addition of myeloperoxidase to the reaction mixture resulted in the detection of hydroxyl radical. Hydroxyl Radical 182-198 myeloperoxidase Homo sapiens 113-128 1314821-10 1992 These results support the ability of human neutrophils and monocytes to generate hydroxyl radical through a myeloperoxidase-dependent mechanism. Hydroxyl Radical 81-97 myeloperoxidase Homo sapiens 108-123