PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1306524-9 1992 Single amino acid substitutions replacing Arg 201 with either Cys or His or Gln 227 with either Arg or Leu cause constitutive activation of adenylyl cyclase by inhibiting GTPase (gsp oncogene). Leucine 103-106 GSM1 Homo sapiens 179-182