PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12807699-1 2004 We tested the hypothesis that the NAD(P)H oxidase-dependent generation of superoxide anion (O2-*) mediates tumor necrosis factor-alpha (TNF)-induced alterations in the permeability of pulmonary microvessel endothelial monolayers (PMEM). Superoxides 74-90 tumor necrosis factor Homo sapiens 107-134 12807699-1 2004 We tested the hypothesis that the NAD(P)H oxidase-dependent generation of superoxide anion (O2-*) mediates tumor necrosis factor-alpha (TNF)-induced alterations in the permeability of pulmonary microvessel endothelial monolayers (PMEM). Superoxides 74-90 tumor necrosis factor Homo sapiens 136-139 12807699-1 2004 We tested the hypothesis that the NAD(P)H oxidase-dependent generation of superoxide anion (O2-*) mediates tumor necrosis factor-alpha (TNF)-induced alterations in the permeability of pulmonary microvessel endothelial monolayers (PMEM). Superoxides 92-94 tumor necrosis factor Homo sapiens 107-134 12807699-1 2004 We tested the hypothesis that the NAD(P)H oxidase-dependent generation of superoxide anion (O2-*) mediates tumor necrosis factor-alpha (TNF)-induced alterations in the permeability of pulmonary microvessel endothelial monolayers (PMEM). Superoxides 92-94 tumor necrosis factor Homo sapiens 136-139 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Oligonucleotides 18-33 calcineurin like EF-hand protein 1 Homo sapiens 0-3 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Oligonucleotides 18-33 tumor necrosis factor Homo sapiens 48-51 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Oligonucleotides 18-33 cytochrome b-245 alpha chain Homo sapiens 0-7 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Oligonucleotides 18-33 neutrophil cytosolic factor 1 Homo sapiens 79-86 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Superoxides 88-90 calcineurin like EF-hand protein 1 Homo sapiens 0-3 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Superoxides 88-90 tumor necrosis factor Homo sapiens 48-51 12807699-6 2004 p22phox antisense oligonucleotide prevented the TNF-induced effect on p22phox, p47phox, O2-*, and permeability. Superoxides 88-90 cytochrome b-245 alpha chain Homo sapiens 0-7 12807699-8 2004 The TNF-induced increase in O2-* and permeability to albumin was also prevented by the O2-* scavenger Cu-Zn superoxide dismutase (100 U/ml). Superoxides 28-30 tumor necrosis factor Homo sapiens 4-7 12807699-8 2004 The TNF-induced increase in O2-* and permeability to albumin was also prevented by the O2-* scavenger Cu-Zn superoxide dismutase (100 U/ml). Superoxides 87-89 tumor necrosis factor Homo sapiens 4-7 12807699-9 2004 The results indicate that the activation of NAD(P)H oxidase, via the generation of O2-*, mediates TNF-induced barrier dysfunction in PMEM. Superoxides 83-85 tumor necrosis factor Homo sapiens 98-101