PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12663670-3 2003 We have observed that four DNA-damaging agents (cisplatin, actinomycin D, MMS, and etoposide), but not the cisplatin isomer, transplatin, which does not readily damage DNA, strongly activate JNK, p38, and extracellular signal-regulated kinase (ERK), and strongly increase phosphorylation and ATF2-dependent transcriptional activity. Methyl Methanesulfonate 74-77 mitogen-activated protein kinase 8 Homo sapiens 191-194