PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12569976-4	2002	METHODS: The effect of arachidonic acid or platelet agonists on LTC4 synthase activity was investigated in platelets obtained from healthy volunteers, aspirin-intolerant asthmatics or aspirin-tolerant asthmatics after in vivo treatment or in vitro pre-incubation with aspirin.	Arachidonic Acid	23-39	leukotriene C4 synthase	Homo sapiens	64-77	
12569976-5	2002	RESULTS: Incubation of normal platelets with arachidonic acid or collagen provoked approximately 50% reduction of platelet LTC4 synthase activity, as determined by the conversion of LTA4 to LTC4.	Arachidonic Acid	45-61	leukotriene C4 synthase	Homo sapiens	123-136	
12569976-7	2002	Arachidonic acid-induced inhibition of LTC4 synthase activity was totally abolished in platelets collected from peripheral blood already 30 min after aspirin ingestion but was fully restored in platelets collected 3 to 7 days after the administration of aspirin.	Arachidonic Acid	0-16	leukotriene C4 synthase	Homo sapiens	39-52	
12569976-10	2002	Similarly, LTC4 synthase activity in platelets from AIA and aspirin-tolerant asthmatics (ATA) was reduced by approximately 50% after pre-treatment with arachidonic acid in vitro.	Arachidonic Acid	152-168	leukotriene C4 synthase	Homo sapiens	11-24