PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12135947-4	2002	Both in vivo and in vitro phosphorylation of endothelial nitric oxide synthase (eNOS) by Akt were reduced by hyperglycemia and hexosamine activation.	Hexosamines	127-137	AKT serine/threonine kinase 1	Homo sapiens	89-92	
12135947-7	2002	CONCLUSIONS: Our data show that hyperglycemia, through the hexosamine pathway, impairs activation of the IR/IRS/PI3-K/Akt pathway, resulting in deregulation of eNOS activity.	Hexosamines	59-69	AKT serine/threonine kinase 1	Homo sapiens	118-121